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Uterine Cancer (Endometrial Cancer)

 

 

Definition

    

     Endometrial cancer is cancer that starts in the endometrium, the lining of the uterus (womb).

Risk Factors

  • Never having been pregnant

  • Obesity

  • Diabetes

  • Polycystic ovarian disease

  • Taking estrogen without Progesterone

  • Tamoxifen -- a medication used for Breast Cancer

Symptoms

  • Abnormal uterine bleeding, abnormal menstrual periods

    • Bleeding between normal periods before menopause

    • Vaginal bleeding or spotting after menopause

  • Extremely long, heavy, or frequent episodes of vaginal bleeding after age 40

  • Lower abdominal pain or pelvic cramping

  • Thin white or clear vaginal discharge after menopause

Screening and Diagnostics

  • Endometrial biopsy

  • Hysteroscopy (scope passed through the cervix into the uterus)

  • Ultrasound

  • MRI

Treatment

  • Total hysterectomy including the ovaries

  • Radiation treatment for more severe cases

  • Progestins for advanced cancers

Complications 

     Complications may include anemia due to blood loss. A perforation (hole) of the uterus may occur during a D and C or endometrial biopsy.

Prevention

     All women should have regular pelvic exams and Pap smears beginning at the onset of sexual activity (or at the age of 20 if not sexually active) to help detect signs of any abnormal development.

     Women with any risk factors for endometrial cancer should be followed more closely by their doctors. Frequent pelvic examinations and screening tests, including a Pap smear and endometrial biopsy, should be done.

     Women who are taking estrogen replacement therapy should also take these precautions.

 

 
 

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