High Blood Pressure or Hypertension is
a measure of the force your heart uses to pump blood
throughout the body and the ability of your blood
vessels to deal with that force.
If your vessels become narrowed, your heart has to
pump harder to maintain circulation, thus exerting
more pressure against the vessel walls. Eventually,
this high pressure will increase your risk of
developing heart disease and stroke
Causes
Some people
develop high blood pressure during pregnancy or
because of hormone imbalances or an illness such as
kidney disease. But for most people, hypertension
can't be traced to a single cause. A family history of
hypertension doubles your chances of having it. High
blood pressure is also more common in older people.
Anyone who doesn't exercise, is overweight, drinks too
much alcohol, or, in some cases, eats too much salt is
at the risk of developing hypertension.
About 90% to 95% of hypertension cases, called
primary, or essential hypertension, have no known
cause. Primary hypertension may be influenced by
factors such as genetic makeup, weight, or salt
intake.
Secondary hypertension is hypertension that is caused
by an underlying medical condition. Secondary
hypertension is the name given to high blood pressure
that has a specific cause, such as a thyroid or a
kidney problem. The most common cause of secondary
hypertension is kidney disease.
Symptoms
People with primary high blood pressure
usually do not have any symptoms. Some people with
hypertension experience occasional headaches; however,
headaches are very common and can be caused by various
other factors.
Most people with high blood pressure feel fine and
only find out they have high blood pressure during a
routine examination or a doctor visit for another
problem.
It is important to have your blood pressure checked, even if you don't
have any symptoms. If untreated, slowly rising blood
pressure can damage your brain, heart, kidneys, or
arteries, and could lead to heart attacks, strokes, or
kidney failure.
Treatment
Treatment for high blood pressure depends on the
severity of the disease and whether you have other
health problems, such as heart failure or diabetes, or
you are pregnant.
If your blood pressure crosses the line into
hypertension, your doctor will probably add medication
to the treatment plan. However, you may be able to get
results with less medication if you continue to follow
the lifestyle changes intended to lower your blood
pressure. Medication is generally prescribed right
away for patients whose blood pressure is high normal
but who also have heart failure, kidney failure, or
diabetes.
Lifestyle changes that may reduce blood pressure
include:
- Low salt diet
- reducing fat intake
- losing weight
- getting regular exercise
- Quit smoking.
- Reduce alcohol consumption.
- Get adequate dietary calcium.
- Control your stress.
If lifestyle changes do not lower your blood
pressure enough, the doctor will begin drug therapy.
- Diuretics or "water pills" (thiazide,
hydrochlorothiazide, chlorathalidone and indapamide)
increase the elimination of salt and water through
urination, thereby lessening blood volume and
pressure.
- Beta-blockers (such as propranolol, atenolol, nadolol,
pindolol and labetolol) lower blood pressure by
reducing the amount of blood pumped by the heart.
If this first line of treatment is ineffective or the
patient has other medical conditions, other types of
medications which may be used:
- Angiotensin converting enzyme (ACE) inhibitors (captopril,
enalapril and lisinopril) lower blood pressure by
blocking the production of a hormone known as
angiotensin, which increases blood pressure.
-
Centrally acting drugs (clonidine and guanabenz)
block the transmission of nerve impulses with the
autonomic nervous system, which controls the
involuntary action of the heart and blood vessels
among other organs.
-
Calcium-channel blockers (nifedipine, nicardipine,
verapamil and diltiazem) relax blood-vessel walls,
thereby lowering pressure.
-
Vasodilators (hydralazine and minoxidil) relax the
smooth muscle of the peripheral arteries, which causes
them to dilate and so reduce the resistance to blood
flow.
-
Alpha-adrenergic antagonists can cause blood pressure
to drop drastically when standing up. It helps in men
with benign prostatic hyperplasia (big prostates), and
is often used in men with both High Blood Pressure and
Enlarged Prostates.
-
Angiotensin II receptor antagonists -- similar to ACE
inhibitors but with fewer side effects. This class of
medicine should not be used in pregnancy since it may
cause fetal abnormalities and death.
Centrally acting -- most commonly used is Clonidine.
Clonidine's biggest danger is that missing doses can
cause severe "rebound" hypertension.