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Gastroesophageal Reflux Disease (GERD)

 


Introduction

Gastroesophageal reflux disease is a chronic condition in which there is a backflow (reflux) of stomach acid into the food pipe (esophagus). GERD is a This constant backwash of acid can irritate the lining of your esophagus, causing it to be irritated and inflamed. It occurs when the LES muscle is very weak or, more commonly, when it inappropriately relaxes causing heartburn. Heartburn is the burning sensation in the throat or chest caused by the backwash of the stomach contents. Almost everyone occasionally experiences a reflux of acid from their stomach into their esophagus. In most people, reflux symptoms are mild and do not last long. With GERD, however, reflux occurs more frequently and causes enough discomfort that the person affected is aware of the condition.

Causes

Various lifestyle and dietary factors can contribute to heartburn by relaxing the lower esophageal sphincter and allowing it to open, increasing the amount of acid in the stomach, increasing stomach pressure, or by making the esophagus more sensitive to harsh acids. These factors include:

  • Eating large portions.
  • Eating certain foods, including onions, chocolate, peppermint, high-fat or spicy foods, citrus fruits, garlic and tomatoes or tomato-based products.
  • Drinking certain beverages, including citrus juices, alcohol and caffeinated and carbonated drinks.
  • Eating before bedtime.
  • Being overweight
  • Smoking
  • Wearing tight fitting clothing or belts
  • Lying down or bending over, especially after eating
    Stress
     

Symptoms

The most common symptoms of GERD are heartburn and regurgitation. These symptoms are most likely to occur 30 to 60 minutes afte meals. The heartburn is usually intensified by eating, lying down and bending over.
Additional, atypical symptoms may include regurgitation of acidic materials, chest pain, asthma, chronic cough, chronic bronchitis, chronic sore throat, morning hoarseness, swallowing difficulty, bloating, belching, nausea and weight loss.

Treatment

For patients with mild GERD, doctors recommend simple lifestyle changes, such as quitting smoking, dietary changes and taking over-the-counter (OTC) antacids.
Physicians suggest eating smaller meals and avoiding acidic foods, fatty foods, peppermint, chocolate and alcohol. Most importantly, it is recommended to avoid eating three hours prior to bedtime or to lying down.
For mild cases, your doctor may prescribe antacids to take after meals and at bedtime.  Antacids have long been a mainstay of treatment of gastroesophageal reflux.  But antacids alone won't heal an inflamed esophagus damaged by stomach acid.

When patients with mild to moderate symptoms of GERD fail to improve with lifestyle changes and antacids, the next step is to try other medications. Doctors may suggest a Histamine2 (H2) receptor antagonist, such as cimetidine (Tagamet), ranitidine (Zantac), famotidine (Pepcid) or nizatidine (Axid), each if which has a moderate ability to suppress acid.They don't act as quickly as antacids, but they provide longer relief. Take these medications before a meal that you think may cause heartburn because it takes them about 30 minutes to work.

 Surgery is only recommended if the symptoms don’t respond to other treatments. Surgery is called a Nissen fundoplication. With the advent of the proton pump and inhibitor medications, surgery is now rarely needed

 

 
 

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