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Alcoholism

 

Definition

     Alcoholism is the consumption of or preoccupation with alcoholic beverages to the extent that this behavior interferes with the alcoholic's normal personal, family, social, or work life. Alcohol consumption caused by alcoholism can result in psychological and physiological conditions, and ultimately in death.

Causes

  • Partial genetic Predisposition -- higher rate in twins and adopted children with alcoholic birth parents
  • Abnormalities in the brain neurotransmitters or chemical enzymes may play a role.
  • Depression
  • Anxiety
  • Addictive personality

Symptoms 

     Men who consume 15 or more drinks a week, women who consume 12 or more drinks a week, or anyone who consumes 5 or more drinks per occasion at least once a week are all at risk for developing alcoholism. (One drink is defined as a 12-ounce bottle of beer, a 5-ounce glass of wine, or a 1 1/2-ounce shot of liquor).

     Some of the symptoms associated with alcoholism include:

  • Drinking alone
  • Making excuses to drink
  • Need for daily or frequent use of alcohol for adequate function
  • Lack of control over drinking, with inability to discontinue or reduce alcohol intake
  • Episodes of violence associated with drinking
  • Secretive behavior to hide alcohol related behavior
  • Hostility when confronted about drinking
  • Neglect of food intake
  • Neglect of physical appearance
  • Nausea and vomiting
  • Shaking in the morning
  • Abdominal pain
  • Numbness and tingling
  • Confusion

     Alcohol withdrawal symptoms vary from mild to severe and may include:

  • Rapid heart rate and sweating
  • Restlessness or agitation
  • Loss of appetite, nausea, or vomiting
  • Confusion or hallucinations
  • Tremors and seizures

Screening and Diagnostics

     All physicians should ask their patients about their drinking. A history may be obtained from family if the affected person is unwilling or unable to answer questions. A physical examination is performed to identify physical problems related to alcohol use.

  • A toxicology screen or blood alcohol level confirms recent alcohol ingestion, which does not necessarily confirm alcoholism.

  • Liver function tests can be elevated. GGPT (glutaryl transaminase) is often elevated more than other liver function tests.

  • CBC (complete blood count) - MCV can be elevated (mean corpuscular volume or size of the red blood cells).

  • Serum magnesium, uric acid, total protein, and folate tests may be abnormal.

Treatment

  • Alcohol recovery programs
  • Alcoholics anonymous
  • Religious/spiritual support
  • Treatment of Depression, if present:
    1. Psychotherapy
    2. Antidepressants
  • Disulfiram (Antabuse) -- an aversion medication that causes nausea/vomiting if one drinks alcoholic beverages
  • Naltrexone -- a medication that helps with alcohol craving
  • Ondansetron -- a medication that helps with alcohol craving
  • Treatment of alcohol withdrawal if it occurs
  • Treating Depression and social problems
  • Treatment goal

- Complete Abstinence (and not "controlled drinking")

Prognosis

     Alcoholism is a major social, economic, and public health problem. Alcohol is involved in more than half of all accidental deaths and almost half of all traffic deaths. A high percentage of suicides involve the use of alcohol in combination with other substances. Additional deaths are related to the long-term medical complications associated with the disease. Only 15% of those with alcohol dependence seek treatment for this disease. Relapse after treatment is common, so it is important to maintain support systems in order to cope with any slips and ensure that they don't turn into complete reversals. Treatment programs have varying success rates, but many people with alcohol dependency have a full recovery.

Complications

  • Pancreatitis
  • Heart muscle damage
  • Nerve damage
  • Esophageal bleeding
  • Brain degeneration
  • Cirrhosis of the liver
  • Delirium tremens (DTs)
  • Depression
  • Erectile dysfunction
  • Fetal alcohol syndrome in the offspring of alcoholic women
  • High blood pressure
  • Increased incidence of cancer
  • Insomnia
  • Nutritional deficiencies
  • Suicide
  • Wernicke-Korsakoff syndrome

Prevention

     Educational programs and medical advice about alcohol abuse have been successful in decreasing alcohol abuse and its associated problems. Alcohol dependency requires more intensive management.

     The National Institute on Alcohol Abuse and Alcoholism recommends that women have no more than 1 drink per day and men no more than 2 drinks per day. One drink is defined as a 12-ounce bottle of beer, a 5-ounce glass of wine, or a 1 1/2-ounce shot of liquor.

 
 

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